I am not sure about the entire race/environment being "disabled" though. Not saying it wouldn't; work, but a very useful literary device is being able to play off the differences of the characters. Each character could indeed have a different disability, but you would lose an angle to play out of these challenges/differences.
Perhaps a team of disabled heroes who have been shunned from other teams due to there disabilities banding together to thwart some dire threat.
Of course the most important thing is continuity.
As a person with a disability myself, I wish you luck.
- Continuity is or it is not. There is no such thing as soft continuity.
- A character IS his continuity.
- Continuity is consistency of the characteristics of people, plot, objects, and places seen by the reader or viewer.