Venom declares his independence and moves to Philadelphia in Venom #28.
Source: Marvel's Venom pulls up NYC stake for Philly steak
Venom will be leaving New York for a fresh start in Philadelphia starting in issue 28 of his solo title. With this new start comes a few new faces including tabloid journalist Katy Kiernan and his new love interest Valkyrie (that was fast).
Writer Cullen Bunn promises that you will see real world Philadephia locations in the book as well as the local legends and history. No word on any antagonists, but the writer promises that for Eugene "Flash" Thompson, life in the City of Brotherly love won't be easy.
Venom #28 hits the streets on December 19, 2012.