Typhoid Mary aka. Mary Walker, is aiming to make a big comeback by targeting Hell's Kitchen in New York in Typhoid Fever: Spider-Man #1. The character is mostly associated with Daredevil, but he's busy right now, so as the title implies, Spider-Man will step in to help this not-so-friendly neighborhood. Spidey won't be alone though, the X-Men and Iron Fist will also be lending a helping hand (we're guessing we'll see 'ol Hornhead in some capacity as well).
The book's editor, Devin Lewis, has this to say about the main villain and the book:
"Typhoid Mary has one of the most dangerous powersets in the Marvel Universe – and writer Clay Mcleod Chapman (EDGE OF VENOMVERSE) is determined to use those powers in ways we've never seen before. Pyrokinesis, telekinesis, and mind control... and that's all in the first scene! Wait'll you see what else Clay has planned, and what artist Stefano Landini has done with the script for TYPHOID FEVER: SPIDER-MAN!"
Typhoid Fever: Spider-Man hits in October.
Typhoid Fever: Spider-Man #1 cover by R.B. Silva